1. Home
  2. USMLE
  3. USMLE Exam Syllabus

USMLE Exam Syllabus

Start Free USMLE Exam Practice After Reviewing the Topics

Before starting your USMLE exam preparation, it is recommended to review the complete USMLE United States Medical Licensing exam syllabus and carefully go through the exam objectives listed below. Once you understand the exam structure and objectives, you should practice using our free USMLE questions. We also provide premium USMLE practice test, fully updated according to the latest exam objectives, to help you accurately assess your preparedness for the actual exam.

USMLE Exam Objectives

Section Objectives
Table 1: Step 1 Test Content Specifications*
  • General Principles
  • Blood & Lymphoreticular/Immune Systems
  • Behavioral Health & Nervous Systems/Special Senses
  • Musculoskeletal, Skin & Subcutaneous Tissue
  • Cardiovascular System
  • Respiratory & Renal/Urinary Systems
  • Gastrointestinal System 
  • Reproductive & Endocrine Systems
  • Multisystem Processes & Disorders
  • Biostatistics & Epidemiology/Population Health
  • Social Sciences: Communication and Interpersonal Skills
Table 2: Step 1 Physician Tasks/Competencies Specifications
  • Medical Knowledge: Applying Foundational Science Concepts
  • Patient Care: Diagnosis
  • History/Physical Examination     
  • Diagnosis     
  • Communication and Interpersonal Skills
  • Practice–based Learning & Improvement
Table 3: Step 1 Discipline Specifications
  • Pathology
  • Physiology
  • Pharmacology
  • Biochemistry & Nutrition
  • Microbiology
  • Immunology
  • Gross Anatomy & Embryology
  • Histology & Cell Biology
  • Behavioral Sciences
  • Genetics
Table 1: Step 2 CK System Specifications*
  • General Principles of Foundational Science
  • Immune System
  • Blood & Lymphoreticular System
  • Behavioral Health
  • Nervous System & Special Senses
  • Musculoskeletal System/Skin & Subcutaneous Tissue   
  • Cardiovascular System    
  • Respiratory System    
  • Gastrointestinal System
  • Renal & Urinary System & Male Reproductive
  • Pregnancy, Childbirth & the Puerperium
  • Female Reproductive System & Breast
  • Endocrine System
  • Multisystem Processes & Disorders
  • Biostatistics & Epidemiology/Population Health/Interpretation of Medical Literature
  • Social Sciences: Legal/Ethical Issues & Professionalism/Systems-based Practice & Patient Safety
Table 2: Step 2 CK Physician Task/Competencies Specifications*
  • Medical Knowledge: Applying Foundational Science Concepts
  • Patient Care: History and Physical Exam
  • Patient Care: Laboratory/Diagnostic Studies
  • Patient Care: Diagnosis
  • Patient Care: Prognosis/Outcome
  • Patient Care: Health Maintenance/Disease Prevention
  • Patient Care: Pharmacotherapy
  • Patient Care: Clinical Interventions
  • Patient Care: Mixed Management
  • Practice-based Learning & Improvement
  • Professionalism
  • Systems-based Practice & Patient Safety
Table 3: Step 2 CK Discipline Specifications
  • Medicine
  • Surgery
  • Pediatrics
  • Obstetrics & Gynecology
  • Psychiatry
Official Information http://www.usmle.org/step-1/#question-formats